Sign in: Staff/Students
A new European research project aiming to help tackle the emergence and spread of drug-resistant superbugs is underway at the University’s Institute of Infection and Global Health.
Funded by the Joint Programming Initiative on Antimicrobial Resistance (JPI-AMR) and led in Liverpool by Professor Aras Kadioglu, the project focuses on AMR in Streptococcus pneumoniae; a major human pathogen causing 1.3 million deaths worldwide annually due to invasive diseases such as pneumonia, meningitis and sepsis.
Effective antibiotics and particularly penicillin are crucial to successfully treat patients infected with pneumococci, but efforts to treat disease in both children and adults have been complicated by increasing resistance to antimicrobials. This increase in resistance is mainly due to over use of antibiotics and clonal expansion and global spread of multi-drug resistant pneumococci.
Epidemiological studies have demonstrated that antibiotic resistance is spread globally by a limited number of particularly successful multi-drug resistant pneumococcal clones. It is not known however, how these resistant pneumococcal clones are acquired or spread globally.
Professor Kadioglu said: “We know that vaccination has certainly decreased AMR among vaccine-covered pneumococcal strains, but AMR now emerges by expansion of non-vaccine covered strains of pneumococci. The goal of our project is to understand the genetic and functional properties of these AMR clones with the aim of targeting and stopping their transmission in the carrier population.”
The €1.6 million funded 3 year JPI-AMR project titled ‘Mechanisms for acquisition and transmission of antimicrobial resistant (AMR) pneumococcal clones pre- and post-vaccination’ brings world leading researchers in the Karolinska Institute, the Institute of Infection Immunology Hannover and the Royal Institute of Technology Stockholm, together with the University of Liverpool.
For more details please see: https://www.liverpool.ac.uk/infection-and-global-health/research/bacterial-pathogenesis-and-immunity/
You must be logged in to post a comment.
All recent news
Liverpool technician wins prestigious Times Higher Education Award
Episode 28: Revisiting resilience: Chronicity and the four pillars of resilience
How to get a COVID-19 test before you travel
New research helps detect change in Arctic Ecosystems
Claim your graduation package
Confused about the rules of England's new #COVID19 tier system? Prof Tom Solomon @runningmadprof and @BBCHughPym helped answer listeners' questions (and there were many!) on @BBCr4today #LivUniCovid
📻 Listen from 2hr 36mins https://www.bbc.co.uk/sounds/play/m000pt9x
"It is gratifying to see technicians being recognised for the work that we do and I hope that my win will inspire others to realise that they can make a difference too.”
Congratulations again to John Waters on his amazing #THEAwards win👏
Full story ➡️ https://bit.ly/36eL7Dw
//VIDEO// ‘Human Chain: Poets on the Poetry of Seamus Heaney’
Bernard O’Donoghue @wadhamoxford, @Gail_McConnell_, @seanehewitt, Tara Bergin @StudentsNCL + Yousif M. Qasmiyeh @RefugeeHosts discuss Heaney + special reading by Bríd Brennan: https://news.liverpool.ac.uk/2020/11/27/institute-of-irish-studies-to-host-human-chain-poets-on-the-poetry-of-seamus-heaney/