The team tested different strains of the keratitis-causing bacterium Pseudomonas aeruginosa for their ability to survive in a commonly used contact lens cleaning solution
Researchers at the University of Liverpool, have found that a bacterial strain associated with severe infections shows enhanced resistance to a common contact lens disinfectant solution.
Each year in the UK, bacterial infections cause around 6,000 cases of a severe eye condition known as microbial keratitis – an inflammation and ulceration of the cornea that can lead to loss of vision.
The use of contact lenses has been identified as a particular risk factor for microbial keratitis.
Researchers from the University and the Royal Liverpool University and Broadgreen NHS Trust tested different strains of the keratitis-causing bacterium Pseudomonas aeruginosa for their ability to survive in a commonly used contact lens cleaning solution.
The team compared nine clinical strains of P. aeruginosa, taken from hospital patients in the UK, with P. aeruginosa strain 9027, the standard strain used by lens solution manufacturers.
There are more than three million people in the UK using contact lenses. This work suggests that this type of bacteria should be included when testing the efficacy of contact lens cleaning solutions to ensure that the procedures are sufficiently robust to kill all P. aeruginosa strains.
Professor of bacteriology, Craig Winstanley, from the University’s Institute of Infection and Global Health, led the research. He said: “Microbial keratitis can be devastating for a patient – it is important that the risk of developing this condition is reduced in contact lens wearers by improving contact lens disinfectant solutions.”
Investigate further strains
The research group plans to investigate further strains to find out how widespread the enhanced bacterial resistance is and to better understand the mechanisms underlying it. This will potentially help in the design of more effective disinfectant procedures.
The research was presented today at the Society for General Microbiology Annual Conference in Liverpool.
Find out more about studying bacteriology on the University Study Pages or follow the Institute of Infection and Global Health on Twitter.
You must be logged in to post a comment.
All recent news
Comment: UK constitutional law expert considers where next for Brexit
‘Movement, Place and Meaning’ free public lecture series launched
$30,000 cash prize in World Challenge competition – deadline closes soon
New survey identifies the social influences in people attending A&E
Recreating the Bombed Out Church
"It was a significant miscalculation for PM to delay original vote until January, losing the government over a month which could have been used to develop a credible ‘plan B’."
UK constitutional law expert, Prof @mjg_constitlaw on where next for #Brexit https://t.co/0E9nMY4Ngg
Professor @louiseckenny addressing the guests at the launch of The Liverpool Centre for Alcohol Research at the beautiful @SGHLpool. The Centre is being established to help respond to the growing problem of #alcohol misuse #LivAlcoholResearch
“In sport, mental health support has generally been reactive…We need to change that culture”– Andrew Bethell, lead researcher for the https://t.co/8Or4NQ3oZ3 study, talks to @MetroUK about the psychological effects of sports injuries https://t.co/rKvunB2opD #mentalhealth