Sign in: Staff/Students
Testing the new Black Box
The University of Liverpool is working with a business which is developing an automated system to reduce the time spent on the painstaking procedure of DNA sample preparation.
The project which involves Skalene Limited, the University’s Centre for Genomic Research is designed to produce the best possible samples from small quantities of swabs and to remove as much of the human labour as possible in the process.
The new device, called the Black Box, takes the DNA and shears the sample down from long strands to much shorter sequences suitable for sequencing. This process results ten times less DNA being used, compared to the conventional method of humans using pipettes. The team is aiming to make it 50 times more efficient in the future – enabling much better sequences to be obtained from smaller samples.
Professor Hall said: “Automating this process is a big leap forward. The new method we are developing is faster, gives better results and is more robust than others available at the moment.”
The new system is also easier to maintain than alternatives, with plastic tubes replacing complex microfluidic chips.
Dr White said: “Working with the University has been vital for making progress given the complex interaction between biology and engineering implicit in the project. As an SME, on our own we didn’t have access to the variety of expertise and facilities present in the CGR.”
You must be logged in to post a comment.
All recent news
New research project to strip carbon and plastic from our homes
Liverpool Pint of Science 2022 – call for speakers
Study shows urban Britain’s potential as a ‘grow your own’ nation
Virtual find a housemate meet-ups and help with student accommodation
Researcher to lead Antarctic expedition to study marine microbiomes and climate link
Setting sail tomorrow, our ocean scientist Prof @altagliabue will lead an Antarctic research expedition for the Tara Ocean Foundation to study the link between marine microbiomes and climate.
Find out more➡️https://bit.ly/3IuZLqr
After a month in space, @MicroAgeUoL's research is now on its way home! 🌎
Our @MicroAgeUoL team's @Space_Station experiments are complete! The muscle cells are now back on ice and (all being well) will return to earth on @SpaceX's Cargo Dragon this weekend for further analysis! 🤞
Read more about this amazing research ➡️ https://bit.ly/MicroAgeLiftOff 🚀